Stem cell treatment for brain injury
Brain injury can be defined as an injury of the brain regardless of age at onset. A brain injury can result in a substantial handicap to the person who sustained the brain injury and can cause various forms of cognitive impairments such as attention, memory or motor disorder. A brain injury can also include any injury that is vascular and where no external factor has directly created the injury. A brain injury is different from a traumatic brain injury as the later occurs when an outside force injures the brain in a traumatic fashion.
The term traumatic brain injury (TBI) refers to injuries to the brain that are caused by some form of traumatic impact. Traumatic brain injuries usually are caused by a blow to the head, violent shaking or penetration of the brain tissue. Depending on the cause and severity of the brain injury, brain damage can be mild, moderate or severe.
Initial symptoms of a traumatic brain injury may include:
Loss of consciousness
In more serious cases of traumatic brain injury, complications can be fatal. While the severity of traumatic brain injuries varies, the long-term effects are often devastating and life-altering.
Traumatic brain injury is sudden, non-congenital physical damage to the brain from an external force that temporarily or permanently disrupts normal brain function. Brain characteristics and functions that can be affected include consciousness, speech and language, memory, mobility, personality and others. Because the brain controls all bodily functions, any damage to the brain, regardless of severity, can impair physical and psychological activity.
Stem Cell Therapy for Brain Injury
In vitro differentiation of stem cells into desired cell types followed by transplantation into affected region may be of particular value in situations in which a specific cell type is selectively lost and its function is to be restored by replacement of a cell population with similar properties. In case of TBI, multiple cell types are needed (neuronal, glial, endothelial, vascular etc.) to restore the function of broadly damaged area.
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